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Revolutionary DNA-edited 'living drug' puts incurable blood cancer into remission

A new study reports results from the first 11 patients

Revolutionary DNA-edited 'living drug' puts incurable blood cancer into remission
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StarsInsider
09/12/2025 09:15 ‧ 6 hours ago | StarsInsider

HEALTH

Diseases

Scientists at UCL and Great Ormond Street Hospital have created a pioneering base-edited T-cell therapy capable of reversing aggressive, once-incurable T-cell leukemia. By precisely altering DNA, healthy donor cells are transformed into targeted, cancer-destroying “living drugs.”

 

In results published on December 8 in The New England Journal of Medicine, 64% of the first 11 patients entered remission, with several remaining cancer-free for years. The treatment offers new hope to patients with no remaining options.

Bone and blood cancers impact millions of people around the world. These are different types of cancers that affect the blood, bone marrow, and lymphatic system. Some are acute and develop rapidly, while others see years pass before patients show any symptoms. 

In this gallery, we delve into the different types of bone and blood cancers, as well as the risk factors, diagnosis, and treatment. Click on to learn more.

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