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In the world of music, marked by larger-than-life personalities and a fair share of substance abuse issues, on-stage meltdowns seem almost par for the course. While a significant number of music's biggest luminaries have managed to weather their turbulent moments unscathed, there have been those who faced substantial repercussions for their erratic performances, outbursts directed at fans, or unfortunate technical mishaps.

It's a sobering truth that many exceptionally talented artists have seen their careers take a nosedive due to a single ill-fated show, one regrettable speech, or even a mere slip-up with a backing track.

Click through the gallery to witness the stories of musicians who unwittingly derailed their own careers under the unforgiving spotlight.

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In 2003, while performing in London, the lead singer of The Dixie Chicks vocalized her opposition to the Iraq War and expressed disapproval of George Bush's presidency. This viewpoint was met with disapproval from their American supporters, who accused them of lacking patriotism and loyalty to the US.

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They faced serious backlash and were widely criticized, with some TV and radio stations even boycotting their music. Their popularity suffered greatly and it took years for them to make a well-deserved comeback as The Chicks.

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The world was left astounded by an unexpected turn of events during an MTV live performance by the R&B duo Milli Vanilli. As they took the stage, their carefully concealed secret unraveled when their vocal backing track experienced an unfortunate glitch. The result was a surreal moment where their hit song 'Girl You Know It's True' repeatedly chanted, "Girl you know! Girl you know!" It was a jaw-dropping revelation that left the audience in disbelief.

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Amid the chaos, panic set in, and Milli Vanilli abruptly exited the stage. The repercussions of this disastrous performance extended far beyond that fateful moment. It laid bare the shocking truth that all of the vocals on their tracks had been recorded by other, uncredited artists. The media scrutiny was relentless, and their once-loyal fanbase felt betrayed. In a crushing turn of events, the duo was compelled to relinquish the Grammy awards they had proudly accepted earlier that year, marking the painful unraveling of their career.

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Ashlee Simpson's widely publicized lip-syncing mishap on 'Saturday Night Live' was a significant musical scandal that received widespread attention. The incident transpired during the start of her second song, revealing a mismatch between the backing track and the live music performed by the band.

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Simpson stood beside the microphone, appearing perplexed as her voice emanated through the speakers. Uncertain of how to proceed, she performed a clumsy dance and departed from the stage. The media mercilessly mocked her afterward, resulting in her music career failing to gain significant traction.

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Robin Thicke's career suffered a catastrophic downfall when he unveiled his 2013 track 'Blurred Lines.' The song faced an avalanche of criticism due to its lyrics, which were widely condemned for their misogynistic undertones that appeared to diminish the significance of consent. Thicke's situation took a turn for the worse as he failed to do himself any favors with his controversial remarks, such as his statement: "People ask, 'Is this degrading to women?' And I respond, 'Absolutely, it is. What a joy it is to degrade a woman.'" These words and actions left an indelible mark on his career, precipitating a sharp decline in his public standing.

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His 2013 VMA performance of the song, featuring a young Miley Cyrus, was nothing short of outrageously sexual and laden with suggestive elements, drawing sharp criticism from all quarters. Shortly after this debacle, Thicke faced the personal turmoil of his wife leaving him. In a desperate attempt to mend both his marriage and career, he released an album bearing his wife's name, hoping to win her back. Sadly, despite his earnest efforts, his attempts at reconciliation in both his personal life and professional pursuits ultimately proved unsuccessful.

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The career of the late Sinéad O'Connor took a permanent hit when she defiantly tore up a photo of Pope John Paul II during a live TV broadcast in 1992. However, she remained resolute and never expressed regret for her actions. In her memoir 'Rememberings,' featured in Rolling Stone, O'Connor shed light on a revelation that went beyond the story she had initially conveyed. While she had cited protesting sexual abuse by the Catholic Church as part of her motivation, the deeper truth emerged: the photo she destroyed was, in fact, her mother's, and she had always harbored the intention of doing so ever since she stumbled upon it hanging on the wall after her mother's passing. “It represented lies and liars and abuse. The type of people who kept these things were devils like my mother," she writes.

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As a Roman Catholic-raised Muslim convert, O'Connor scoffed in her memoir at the Pope's declaration that he loved the young people of Ireland. "Nobody loved us. Not even God. Sure, even our mothers and fathers couldn’t stand us." For many viewers, O'Connor's actions were perceived more as an anti-Catholic statement than a protest against the recently exposed misconduct within the Church. This interpretation had a profound impact on her popularity and sales in the United States, resulting in a significant decline. Her career never fully recovered from the aftermath of that incident, marking a lasting change in her professional trajectory.

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Although he is credited with introducing the blues to Britain, Eric Clapton appeared to have a limited knowledge of the genre's history.

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In a shocking turn of events during a 1976 concert, he embarked on a disturbing racist tirade from the stage. He declared that all foreigners should leave from England and urged his fans to support a far-right political party, even invoking the incendiary phrase "keep Britain white." This deeply disheartened a substantial portion of his fan base and dealt a severe blow to his reputation, causing lasting damage that would take a considerable amount of time to mend.

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Guns N’ Roses are widely regarded as rock icons. However, their behavior during concerts has caused them to lose the admiration of many fans. There have been numerous instances where they appeared unprepared or under the influence. In more serious cases, Axl Rose has exhibited diva-like behavior and even turned hostile towards the audience.

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Known for their tardiness, this band has been known to keep their loyal fans waiting for hours at their concerts. Axl faced backlash from the crowd in 2010 during a Dublin show due to his unfavorable behavior towards the audience.

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Fergie's solo career post-Black Eyed Peas never quite reached the heights many had expected. However, her performance of the national anthem at the 2018 NBA All-Star game stands out as a particularly damaging moment. Her rendition of 'The Star-Spangled Banner' was widely criticized as being extremely difficult to listen to, and it even led to some players visibly trying to stifle their laughter during the performance.

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In case anyone has forgotten, Lindsay Lohan attempted a career in the music industry during the early 2000s. The response to her songs was varied, but things took a turn for the worse when she appeared on 'Good Morning America' and it was quite evident that she was lip-syncing.

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The R&B star came perilously close to derailing his career with a single incident at the 2013 BBMA's. In a daring stunt, he tried to leap over the crowd from one part of the stage to another, but the move went horribly wrong, resulting in him landing on top of two unsuspecting fans. One of the fans, who suffered injuries as a result, subsequently filed a lawsuit, casting a shadow over his career.

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Scott Stapp, the lead singer, of Creed has gained a reputation for disrupting performances, supposedly as a result of his struggles with substance abuse. On several occasions, he has forced the band to finish shows prematurely, showcased erratic behavior onstage, or delivered such subpar performances that fans requested refunds.

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In the year 2003, an astonishing turn of events saw four concertgoers taking legal action against the band due to the abysmal quality of their performance. These dissatisfied attendees sought refunds not only for their tickets but also for their parking fees. The reason? Scott Stapp, the band's frontman, consistently left the stage for extended periods during songs, engaged in bizarre behavior like rolling on the ground, and even, at one point, passed out. This unfortunate episode had a significantly detrimental impact on the band's reputation and their standing in the eyes of their fanbase.

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The Sex Pistols embarked on a North American tour at the peak of their popularity, ultimately leading to their disbandment. Strained relationships and evident tension among the band members became apparent during their performances.

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After a show in San Francisco that marked the end of their tour, the lead vocalist Johnny Rotten engaged in continuous mockery of the audience during their performance, barely participating in the songs. The following day, he flew to New York and officially declared his departure from The Sex Pistols.

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The Family Stone, under the charismatic leadership of Sly Stone, commanded immense respect as one of the most esteemed funk outfits of the 1970s. Regrettably, their track record for reliability left much to be desired. It was not uncommon for them to arrive at concerts with key band members conspicuously absent, occasionally flat-out refusing to take the stage, or, distressingly, experiencing incidents of incapacitation due to substance abuse. In a particularly disheartening turn of events, Sly Stone ventured to perform solo at Coachella in 2010, delivering a performance while in a completely incoherent state.

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The British boyband Blue enjoyed significant popularity in the UK during the early 2000s and stood on the cusp of securing a major record deal in the United States, a move that could have propelled them to the next level of stardom. Tragically, their prospects took a nosedive when one of their own, Lee Ryan, made insensitive comments regarding the tragic events of 9/11, effectively sabotaging their chances of success in the American market.

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During an interview with The Sun, he said “Who gives a [expletive] about New York when elephants are being killed….Animals need saving and that's more important. This New York thing is being blown out of all proportion."

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The Replacements were a band that transitioned from punk to alternative music during the 1980s. They were known for their fondness of alcohol, and their live performances were often characterized as boozy karaoke sessions.

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Their ill-fated appearance on 'Saturday Night Live' added another layer to the string of misfortunes. The band, notorious for their rowdy behavior, lived up to their reputation and then some. Reports circulated that they had indulged in excessive drinking and substance use prior to taking the stage. The chaos escalated when Bob Stinson, inebriated and high, stumbled and broke his guitar while making his way to the stage. Once the show began, they proceeded to deliver a completely off-key performance, punctuated by a flurry of expletives, all of which unfolded on live television. This episode solidified their status as one of the show's messiest and rowdiest guests in history.

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Karmin, a well-known duo and couple, gained popularity on YouTube for their cover songs. Their performance on ‘Saturday Night Live’ in 2012 received negative feedback from viewers who believed they lacked stage presence and personality. It was suggested that they should have continued focusing on their YouTube channel.

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Another ‘Saturday Night Live’ failure, rock band Greta Van Fleet bombed on the show in 2019. They all appeared extremely nervous and awkward on stage, the sound was poor, and the whole act seemed unrehearsed. They received extremely poor press after their performance and definitely didn’t live up to previous comparisons with Led Zeppelin!

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The Everly Brothers, a renowned duo in the country-rock genre, gained popularity in the United States during the 1950s and 1960s. Despite experiencing a gradual decline in their careers, their fate was sealed when a significant performance in 1973 marked their ultimate downfall.

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Phil Everley showed up to a gig and was furious to discover that his brother Don was completely drunk. The booker had to stop that show shortly after it started because Don was unable to perform. Phil smashed his guitar on stage and walked out, while Don announced that he was done with being an Everly Brother.