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Celine Dion -

Songstress Celine Dion broke some difficult news to her fans in an Instagram video on December 8. "Recently I've been diagnosed with a very rare neurological disorder called Stiff Person Syndrome which affects something like one-in-a-million people," she explained. The rare condition is incurable and causes uncontrollable muscle spasms, making it difficult for her to walk and sing. "It's been really difficult for me to face these challenges and to talk about everything that I've been going through," she shared. Dion revealed that she will not be able to continue the European leg of her tour which was due to restart in February 2023 due to her current physical state. "I always give 100% when I do my show, but my condition is not allowing me to give you that right now." She broke into tears as she signed off, thanking her fans for their support while she works on her recovery and rebuilding her strength. 

Unfortunately, Stiff Person Syndrome is a rare illness that isn't well understood. The muscle spasms come with an extreme sensitivity to stimuli like noise, touch, and emotional distress. Some people with the illness are unable to walk and others choose not to leave the house for fear of a loud noise or unexpected situation triggering a fit of muscle spasms. There is no cure for the disease but treatments like anti-anxiety medication and muscle relaxants can slow its progress and return some quality of life. 

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Roberta Flack -

Grammy-winning singer Roberta Flack has ALS (amyotrophic lateral sclerosis), commonly known as Lou Gehrig's disease, and can no longer sing, her representative said November 14. The degenerative disease, which she was diagnosed with in August, "has made it impossible to sing and not easy to speak," Flack's manager Suzanne Koga told the Associated Press. The disease eventually causes the loss of the ability to speak, eat, walk and breathe, according to The Mayo Clinic, and there is no cure yet. Flack, most famous for hits like 'Killing Me Softly With His Song' and 'The First Time I Ever Saw Your Face' is also 85 years old, "But it will take a lot more than ALS to silence this icon," as her manager said. "Miss Flack plans to stay active in her musical and creative pursuits. Her fortitude and joyful embrace of music that lifted her from modest circumstances to the international spotlight remain vibrant and inspired." Earlier in 2022, Flack had revealed plans to tour again after surviving a 2016 stroke and a battle with COVID-19.

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Ashton Kutcher -

On August 8, Access Hollywood shared a sneak peek of the actor's appearance on 'Running Wild with Bear Grylls,' in which he details his rare condition publicly for the first time: "Like two years ago, I had this weird, super rare form of vasculitis, that like knocked out my vision, it knocked out my hearing, it knocked out like all my equilibrium," he told host Bear Grylls of the disorder. "It took me like a year to build it all back up."

The actor continued, "You don't really appreciate it until it's gone. Until you go, 'I don't know if I'm ever going to be able to see again, I don't know if I'm ever going to be able to hear again, I don't know if I'm ever going to be able to walk again.'" He noted that he's "lucky to be alive" and that through this experience he's learned to "start seeing your obstacles as things that are made for you, to give you what you need," because then "You start surfing on top of your problems instead of living underneath them."

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Mandy Moore -

Mandy Moore revealed that a rare blood disorder prevented her from getting an epidural while giving birth to her second child. “My platelets are too low for an epidural,” the actress told TODAY Parents on July 29, revealing that she suffers from immune thrombocytopenic purpura (ITP). According to the Mayo Clinic, ITP occurs when the immune system “attacks and destroys platelets,” which, if not considered during pregnancy, could lead to dangerous bleeding during delivery. 

Moore already gave birth unmedicated once, the labor for which she described as “awful," but, she said, "I can do it one more time. I can climb that mountain again." She continued, “I wish medication was an option—just the idea of it being on the table is so nice. But we’ll just push forth like we did last time.”

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Sia - The singer suffers from both Graves' disease, an autoimmune disease that results in irregular thyroid function, and Ehlers-Danlos syndrome, which is a group of connective tissue disorders that affect the skin.

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Selena Gomez - The singer and actress is known to suffer from lupus.

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Sarah Hyland - The 'Modern Family' actress suffers from kidney dysplasia.

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Kanye West - In 2018, West opened up about his mental health, revealing that he's bipolar.

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Pamela Anderson - The actress used to suffer from Hepatitis C, which she contracted from using a contaminated tattoo needle. She has been cured since 2015, however.

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Ashley Olsen - The actress suffers from Lyme disease, which can result in debilitating life-long symptoms. A surprisingly large number of celebrities have also struggled with the illness.

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Avril Lavigne - The singer has also suffered from Lyme disease.

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Gigi Hadid - The American model revealed on social media that she suffers from Hashimoto's disease, a chronic illness that affects the thyroid.

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Bella Hadid - Gigi's sister and fellow model Bella Hadid revealed that she has also suffered from Lyme disease.

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Jimmy Kimmel - The presenter has disclosed in interviews that he suffers from narcolepsy.

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Venus Williams - The athlete has been diagnosed with Sjögren's syndrome, an autoimmune disease.

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Michael J. Fox - The actor suffers from Parkinson's. He famously created a foundation to help find ways to combat the disease, called the Michael J. Fox Foundation for Parkinson's Research.

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Lil Wayne - The rapper has revealed that he suffers from epilepsy, which is frequently characterized by its resulting seizures.

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Kristin Chenoweth - The actress has disclosed in interviews that she suffers from Ménière's disease, an inner ear disorder that can cause tinnitus and vertigo.

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Cher - The singer has disclosed that she has the Epstein-Barr virus, and has been suffering from it for decades.

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Nick Cannon - The entertainer suffers from lupus, which has resulted in kidney problems.

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Jack Osbourne - The former reality star suffers from multiple sclerosis, a potentially disabling disease.

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Katie Leclerc -

The actress revealed that she also suffers from Ménière's disease.

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Toni Braxton - The singer revealed that she suffers from lupus.

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Thalía - The singer suffers from the effects of Lyme disease.

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Elisabeth Hasselbeck - The former TV presenter suffers from celiac disease, an autoimmune disease.

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Justin Bieber -

The singer announced in early 2020 that he suffers from both Lyme disease and infectious mononucleosis, otherwise known as glandular fever.

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George Clooney -

When he was at school, the ‘Ocean’s Eleven’ star suffered with Bell’s Palsy, a condition that causes partial paralysis of the face.

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Angelina Jolie -

She has a defective BRCA1 gene, which increases the likelihood of developing certain cancers.

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Kim Kardashian -

Since the age of 30, the reality TV mogul has been suffering with psoriasis, an auto-immune disease that results in patches of abnormal skin.

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Lady Gaga -

The singer was forced to cancel a number of shows in 2012 because she was suffering from synovitis, which involves inflammation of the joints.

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Gaten Matarazzo -

The ‘Stranger Things’ actor suffers with cleidocranial dysplasia, which causes collarbones to be poorly developed or absent, and teeth to be abnormal.

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Missy Elliott -

In 2011, the performer announced that she suffers with Graves’ disease.

See also: Missy Elliott's most iconic moments

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