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See Also
See Again
© Shutterstock
0 / 31 Fotos
Neuromuscular disorders
- Neuromuscular disorders include a wide range of diseases affecting the peripheral nervous system, which consists of all the motor and sensory nerves that connect the brain and spinal cord to the rest of the body. Muscular dystrophy is a rare type of neuromuscular disease.
© Shutterstock
1 / 31 Fotos
Muscular dystrophy
- Muscular dystrophy (MD) is a group of inherited diseases that cause weakness and loss of muscle mass. In muscular dystrophy, abnormal genes (mutations) interfere with the production of proteins needed to form healthy muscle. It's a progressive condition characterized by eventual loss of strength, increasing disability, and possible deformity. There are nine types of MD.
© Shutterstock
2 / 31 Fotos
Congenital muscular dystrophy
- Congenital muscular dystrophy (CMD) refers to a group of muscular dystrophies that become apparent at or near birth. Symptoms include general muscle weakness and possible joint deformities. CMD progresses slowly and shortens lifespan.
© Shutterstock
3 / 31 Fotos
Duchenne muscular dystrophy
- Duchenne muscular dystrophy (DMD) is one of the most severe forms of inherited muscular dystrophies. Seen almost exclusively in males (it rarely affects females, who have much milder symptoms and a better prognosis), onset of DMD is age two to six years. It's characterized by general muscle weakness and wasting, and eventually involves all voluntary muscles. Survival beyond one's twenties is rare.
© Shutterstock
4 / 31 Fotos
Becker muscular dystrophy
- Symptoms of Becker muscular dystrophy (BMD) are almost identical to CMD. Progressive muscle weakness, most notably of the proximal lower limbs, is the primary manifestation of this condition. The onset of BMD symptoms varies widely, between five and 60 years of age, and, like DMD, it's almost always limited to males.
© Shutterstock
5 / 31 Fotos
Distal muscular dystrophy
- Onset of distal muscular dystrophy (DMD) is anywhere between 40 to 60 years of age. Symptoms of DMD include weakness and wasting of muscles of the hands, forearms, and lower legs. However, total incapacity is rare.
© Shutterstock
6 / 31 Fotos
Emery-Dreifuss muscular dystrophy
- Named for Alan Emery and Fritz Dreifuss, physicians who first described the disorder among a Virginia family in the 1960s, Emery-Dreifuss muscular dystrophy (EDMD) targets the shoulder, upper arm, and shin muscles. Joint deformities are common. Onset is usually apparent in childhood and, while progression of EDMD is slow, sudden death may occur from cardiac problems.
© Shutterstock
7 / 31 Fotos
Facioscapulohumeral muscular dystrophy
- Facioscapulohumeral muscular dystrophy (FSHD) affects the muscles of the face, shoulders, upper arms, and lower legs. Age of onset is childhood to early adulthood. Progression of FSHD can be unpredictable: it can be slow but with rapid periods of deterioration.
© Shutterstock
8 / 31 Fotos
Limb-girdle muscular dystrophy
- Limb-girdle muscular dystrophy (LGMD) causes weakness in the shoulder and pelvic girdle. Onset of LGMD is late childhood to middle age. But life expectancy is generally within a normal range because the heart and breathing muscles are usually not affected.
© Shutterstock
9 / 31 Fotos
Myotonic muscular dystrophy
- A common multi-system disorder that affects all muscle groups and many other organs in the body, myotonic muscular dystrophy (MMD) appears anywhere between 20 to 40 years of age. Progression is slow, sometimes spanning 50 to 60 years.
© Shutterstock
10 / 31 Fotos
Oculopharyngeal muscular dystrophy
- Oculopharyngeal muscular dystrophy (OPMD) symptoms include weakening of throat muscles, which, in time, causes inability to swallow and emaciation from lack of food. Onset is 40 to 70 years, and progression is slow.
© Shutterstock
11 / 31 Fotos
Other neuromuscular diseases
- There are numerous other types of neuromuscular diseases. One of the better known neuromuscular diseases is amyotrophic lateral sclerosis (ALS), or motor neurone disease.
© Shutterstock
12 / 31 Fotos
Motor neurone disease
- Early symptoms of motor neurone disease can include weakness in the ankle or leg, slurred speech, or a weak grip. Weakness gets worse over time, inhibiting walking, speaking, and breathing. Life expectancy after diagnosis is one to five years.
© Shutterstock
13 / 31 Fotos
Spinal muscular atrophies
- Spinal muscular atrophy (SMA) is a disorder affecting the motor neurons—nerve cells that control voluntary muscle movement. The condition ranges through infantile progressive spinal muscular atrophy, intermediate spinal muscular atrophy, juvenile spinal muscular atrophy, and adult spinal muscular atrophy.
© Shutterstock
14 / 31 Fotos
Inflammatory myopathies
- The inflammatory myopathies are a group of rare diseases that involve chronic muscle inflammation, muscle weakness, and, in some cases, muscle pain. Myopathy, incidentally, is a general term used to describe a number of conditions affecting the muscles.
© Shutterstock
15 / 31 Fotos
Dermatomyositis
- Dermatomyositis is one of these rare conditions. It causes muscle weakness and skin rash, and inhibits talking or swallowing. There is no cure, but treatment is available to reduce symptoms.
© Getty Images
16 / 31 Fotos
Polymyositis
- Polymyositis is another disease in the inflammatory myopathy group of diseases. Polymyositis is a condition that causes skeletal muscle to become irritated and inflamed, leading to pain, stiffness, and weakness.
© Shutterstock
17 / 31 Fotos
Inclusion body myositis
- Inclusion body myositis (IBM) is a muscle-wasting condition, which causes muscles to become thin and weak. Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier. IBM occurs more frequently in men than in women. There is no cure for the disorder.
© Shutterstock
18 / 31 Fotos
Disorders of the neuromuscular junction
- The body's neuromuscular system includes all the muscles in the body and the nerves connecting them. Disorders of the neuromuscular junction decrease the nerve's activity, causing weakness.
© Shutterstock
19 / 31 Fotos
Myasthenia gravis
- Myasthenia gravis (MG) is a common disease of the neuromuscular junction. It's a long-term condition that commonly affects the muscles that control the eyes and eyelids, facial expressions, chewing, swallowing, and speaking. It can affect people of any age.
© Shutterstock
20 / 31 Fotos
Lambert-Eaton syndrome
- The main symptoms of Lambert-Eaton syndrome are weakness in the legs, arms, neck, and face, as well as problems with automatic body functions, such as controlling blood pressure. It's a rare autoimmune disorder, the majority of cases of which are associated with small cell lung cancer.
© Shutterstock
21 / 31 Fotos
Botulism
- Botulism is a rare but serious illness caused by a toxin that attacks the body's nerves. This, in turn, causes breathing difficulties, muscle paralysis, and even death.
© Shutterstock
22 / 31 Fotos
Rhabdomyolysis
- Rhabdomyolysis is a rare muscle injury where muscles break down due to muscle tissue releasing its proteins and electrolytes into the blood. These substances can damage the heart and kidneys and cause permanent disability or even death.
© Shutterstock
23 / 31 Fotos
Cardiomyopathy
- Cardiomyopathy is a disease that affects your myocardium (heart muscle). It's considered a chronic disease and can worsen over time. However, early diagnosis and treatment may improve overall outlook and extend lifespan.
© Shutterstock
24 / 31 Fotos
Sarcopenia
- Sarcopenia is a reduction in skeletal muscle mass due to aging and/or mobility. The condition is a leading cause of frailty.
© Shutterstock
25 / 31 Fotos
Fibromyalgia syndrome
- An often misunderstood disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues, fibromyalgia syndrome is a chronic condition with no cure.
© Shutterstock
26 / 31 Fotos
Tendinosis
- Tendinosis refers to hardening, thickening, and scarring of the tendons often due to repeatedly suffering smaller injuries that don't heal correctly. The tendons are thick, fibrous tissues that attach your muscles to your joints.
© Shutterstock
27 / 31 Fotos
Metabolic diseases of the muscle
- Metabolic diseases of the muscle can affect all the body's voluntary muscles, such as those in the arms, legs, and trunk. There are 10 primary types of this condition. Among these is acid maltase deficiency. Also known as Pompe disease, it's a genetically inherited disease that affects muscle function.
© Shutterstock
28 / 31 Fotos
Debrancher enzyme deficiency
- Debrancher enzyme deficiency is another metabolic disease of the muscle. Also known as Cori or Forbes disease, this condition interferes with the processing of food (in this case, carbohydrates) for energy production.
© Shutterstock
29 / 31 Fotos
Tetanus
- Elsewhere, tetanus is a serious, life-threatening condition caused by bacteria getting into a wound. Symptoms include painful muscle contractions and the locking of the neck and jaw muscles, which is why tetanus is also known as lockjaw. Sources: (Muscular Dystrophy Association) (Verywell Health) (Cedars-Sinai) (MedlinePlus) (Johns Hopkins Medicine) (National Institute of Neurological Disorders and Stroke) (NHS) (National Institutes of Health)
© Shutterstock
30 / 31 Fotos
© Shutterstock
0 / 31 Fotos
Neuromuscular disorders
- Neuromuscular disorders include a wide range of diseases affecting the peripheral nervous system, which consists of all the motor and sensory nerves that connect the brain and spinal cord to the rest of the body. Muscular dystrophy is a rare type of neuromuscular disease.
© Shutterstock
1 / 31 Fotos
Muscular dystrophy
- Muscular dystrophy (MD) is a group of inherited diseases that cause weakness and loss of muscle mass. In muscular dystrophy, abnormal genes (mutations) interfere with the production of proteins needed to form healthy muscle. It's a progressive condition characterized by eventual loss of strength, increasing disability, and possible deformity. There are nine types of MD.
© Shutterstock
2 / 31 Fotos
Congenital muscular dystrophy
- Congenital muscular dystrophy (CMD) refers to a group of muscular dystrophies that become apparent at or near birth. Symptoms include general muscle weakness and possible joint deformities. CMD progresses slowly and shortens lifespan.
© Shutterstock
3 / 31 Fotos
Duchenne muscular dystrophy
- Duchenne muscular dystrophy (DMD) is one of the most severe forms of inherited muscular dystrophies. Seen almost exclusively in males (it rarely affects females, who have much milder symptoms and a better prognosis), onset of DMD is age two to six years. It's characterized by general muscle weakness and wasting, and eventually involves all voluntary muscles. Survival beyond one's twenties is rare.
© Shutterstock
4 / 31 Fotos
Becker muscular dystrophy
- Symptoms of Becker muscular dystrophy (BMD) are almost identical to CMD. Progressive muscle weakness, most notably of the proximal lower limbs, is the primary manifestation of this condition. The onset of BMD symptoms varies widely, between five and 60 years of age, and, like DMD, it's almost always limited to males.
© Shutterstock
5 / 31 Fotos
Distal muscular dystrophy
- Onset of distal muscular dystrophy (DMD) is anywhere between 40 to 60 years of age. Symptoms of DMD include weakness and wasting of muscles of the hands, forearms, and lower legs. However, total incapacity is rare.
© Shutterstock
6 / 31 Fotos
Emery-Dreifuss muscular dystrophy
- Named for Alan Emery and Fritz Dreifuss, physicians who first described the disorder among a Virginia family in the 1960s, Emery-Dreifuss muscular dystrophy (EDMD) targets the shoulder, upper arm, and shin muscles. Joint deformities are common. Onset is usually apparent in childhood and, while progression of EDMD is slow, sudden death may occur from cardiac problems.
© Shutterstock
7 / 31 Fotos
Facioscapulohumeral muscular dystrophy
- Facioscapulohumeral muscular dystrophy (FSHD) affects the muscles of the face, shoulders, upper arms, and lower legs. Age of onset is childhood to early adulthood. Progression of FSHD can be unpredictable: it can be slow but with rapid periods of deterioration.
© Shutterstock
8 / 31 Fotos
Limb-girdle muscular dystrophy
- Limb-girdle muscular dystrophy (LGMD) causes weakness in the shoulder and pelvic girdle. Onset of LGMD is late childhood to middle age. But life expectancy is generally within a normal range because the heart and breathing muscles are usually not affected.
© Shutterstock
9 / 31 Fotos
Myotonic muscular dystrophy
- A common multi-system disorder that affects all muscle groups and many other organs in the body, myotonic muscular dystrophy (MMD) appears anywhere between 20 to 40 years of age. Progression is slow, sometimes spanning 50 to 60 years.
© Shutterstock
10 / 31 Fotos
Oculopharyngeal muscular dystrophy
- Oculopharyngeal muscular dystrophy (OPMD) symptoms include weakening of throat muscles, which, in time, causes inability to swallow and emaciation from lack of food. Onset is 40 to 70 years, and progression is slow.
© Shutterstock
11 / 31 Fotos
Other neuromuscular diseases
- There are numerous other types of neuromuscular diseases. One of the better known neuromuscular diseases is amyotrophic lateral sclerosis (ALS), or motor neurone disease.
© Shutterstock
12 / 31 Fotos
Motor neurone disease
- Early symptoms of motor neurone disease can include weakness in the ankle or leg, slurred speech, or a weak grip. Weakness gets worse over time, inhibiting walking, speaking, and breathing. Life expectancy after diagnosis is one to five years.
© Shutterstock
13 / 31 Fotos
Spinal muscular atrophies
- Spinal muscular atrophy (SMA) is a disorder affecting the motor neurons—nerve cells that control voluntary muscle movement. The condition ranges through infantile progressive spinal muscular atrophy, intermediate spinal muscular atrophy, juvenile spinal muscular atrophy, and adult spinal muscular atrophy.
© Shutterstock
14 / 31 Fotos
Inflammatory myopathies
- The inflammatory myopathies are a group of rare diseases that involve chronic muscle inflammation, muscle weakness, and, in some cases, muscle pain. Myopathy, incidentally, is a general term used to describe a number of conditions affecting the muscles.
© Shutterstock
15 / 31 Fotos
Dermatomyositis
- Dermatomyositis is one of these rare conditions. It causes muscle weakness and skin rash, and inhibits talking or swallowing. There is no cure, but treatment is available to reduce symptoms.
© Getty Images
16 / 31 Fotos
Polymyositis
- Polymyositis is another disease in the inflammatory myopathy group of diseases. Polymyositis is a condition that causes skeletal muscle to become irritated and inflamed, leading to pain, stiffness, and weakness.
© Shutterstock
17 / 31 Fotos
Inclusion body myositis
- Inclusion body myositis (IBM) is a muscle-wasting condition, which causes muscles to become thin and weak. Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier. IBM occurs more frequently in men than in women. There is no cure for the disorder.
© Shutterstock
18 / 31 Fotos
Disorders of the neuromuscular junction
- The body's neuromuscular system includes all the muscles in the body and the nerves connecting them. Disorders of the neuromuscular junction decrease the nerve's activity, causing weakness.
© Shutterstock
19 / 31 Fotos
Myasthenia gravis
- Myasthenia gravis (MG) is a common disease of the neuromuscular junction. It's a long-term condition that commonly affects the muscles that control the eyes and eyelids, facial expressions, chewing, swallowing, and speaking. It can affect people of any age.
© Shutterstock
20 / 31 Fotos
Lambert-Eaton syndrome
- The main symptoms of Lambert-Eaton syndrome are weakness in the legs, arms, neck, and face, as well as problems with automatic body functions, such as controlling blood pressure. It's a rare autoimmune disorder, the majority of cases of which are associated with small cell lung cancer.
© Shutterstock
21 / 31 Fotos
Botulism
- Botulism is a rare but serious illness caused by a toxin that attacks the body's nerves. This, in turn, causes breathing difficulties, muscle paralysis, and even death.
© Shutterstock
22 / 31 Fotos
Rhabdomyolysis
- Rhabdomyolysis is a rare muscle injury where muscles break down due to muscle tissue releasing its proteins and electrolytes into the blood. These substances can damage the heart and kidneys and cause permanent disability or even death.
© Shutterstock
23 / 31 Fotos
Cardiomyopathy
- Cardiomyopathy is a disease that affects your myocardium (heart muscle). It's considered a chronic disease and can worsen over time. However, early diagnosis and treatment may improve overall outlook and extend lifespan.
© Shutterstock
24 / 31 Fotos
Sarcopenia
- Sarcopenia is a reduction in skeletal muscle mass due to aging and/or mobility. The condition is a leading cause of frailty.
© Shutterstock
25 / 31 Fotos
Fibromyalgia syndrome
- An often misunderstood disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues, fibromyalgia syndrome is a chronic condition with no cure.
© Shutterstock
26 / 31 Fotos
Tendinosis
- Tendinosis refers to hardening, thickening, and scarring of the tendons often due to repeatedly suffering smaller injuries that don't heal correctly. The tendons are thick, fibrous tissues that attach your muscles to your joints.
© Shutterstock
27 / 31 Fotos
Metabolic diseases of the muscle
- Metabolic diseases of the muscle can affect all the body's voluntary muscles, such as those in the arms, legs, and trunk. There are 10 primary types of this condition. Among these is acid maltase deficiency. Also known as Pompe disease, it's a genetically inherited disease that affects muscle function.
© Shutterstock
28 / 31 Fotos
Debrancher enzyme deficiency
- Debrancher enzyme deficiency is another metabolic disease of the muscle. Also known as Cori or Forbes disease, this condition interferes with the processing of food (in this case, carbohydrates) for energy production.
© Shutterstock
29 / 31 Fotos
Tetanus
- Elsewhere, tetanus is a serious, life-threatening condition caused by bacteria getting into a wound. Symptoms include painful muscle contractions and the locking of the neck and jaw muscles, which is why tetanus is also known as lockjaw. Sources: (Muscular Dystrophy Association) (Verywell Health) (Cedars-Sinai) (MedlinePlus) (Johns Hopkins Medicine) (National Institute of Neurological Disorders and Stroke) (NHS) (National Institutes of Health)
© Shutterstock
30 / 31 Fotos
Do you know these muscle-disrupting diseases?
What are the most debilitating muscular system disorders?
© Shutterstock
Diseases of the muscles are numerous. Sadly, most of them are distressing, and in some cases life-threatening. Muscles literally hold our bodies together. They also move and support our organs. Weakness or the wasting away of muscle tissue can seriously inhibit mobility and our ability to breathe properly. Symptoms typically include aches, pains, and increasing disability. Deformity is not uncommon. And in the most extreme cases, a disease of the muscular system often ends in death. So, what are the most debilitating muscle disorders and their consequences?
Click through and find out more about the diseases that mess with muscles.
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