'Grey's Anatomy' and 'Euphoria' star Eric Dane made an emotional return to television this week, guest-starring on NBC’s ‘Brilliant Minds’ as Matthew, a firefighter grappling with amyotrophic lateral sclerosis (ALS). The role mirrors Dane’s own diagnosis, which he publicly revealed in April.
Showrunner Michael Grassi said Dane’s team reached out expressing interest in the series. “I was so excited by the opportunity to tell a story with him and what he’s currently dealing with,” Grassi told Deadline.
Dane’s performance marks one of his most personal roles yet, blending art with advocacy while spotlighting the realities of living with ALS—a degenerative disease that gradually causes individuals to lose the use of their limbs.
Intrigued? Click through the following gallery and explore the causes, symptoms, and treatment options for ALS.