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The dual role of scratching: inflammation and immune defense

New report unlocks the hidden benefits and drawbacks

The dual role of scratching: inflammation and immune defense
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Gabrielle Sanderson
11/04/2025 10:15 ‧ 2 months ago | StarsInsider

HEALTH

Science

Is there anything that offers temporary bliss more than scratching a relentless itch? In a newly published report, scientists believe they have discovered the biological reason why we feel such satisfying relief when we scratch, but also how it almost always leads to worsened inflammation... at least in mice. While scratching is commonly associated with the aggravation of skin conditions such as eczema, fungal infections, chickenpox, and insect bites, recent research from the University of Pittsburgh reveals that it may also play a crucial role in enhancing immune defenses against bacterial infections.

This dual nature of scratching, both harmful and beneficial, suggests that it is not merely a counterproductive reaction, but rather an evolutionary adaptation with deeper biological significance. In this gallery we investigate. Click to the next image to dive in.

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