Depression, whether major depressive disorder, treatment‑resistant, or bipolar, remains one of the world’s leading causes of disability. For decades, first‑line antidepressants have offered only partial relief, often taking weeks to show effect. That gap has fueled growing interest in faster, more innovative approaches.
One surprising candidate is nitrous oxide, better known as “laughing gas.” Early clinical trials suggest it can deliver rapid, short‑term improvements for patients who haven’t responded to standard medications. Meta‑analyses show benefits after a single dose, with longer relief from repeated treatments. Side effects appear mild and brief, though experts emphasize the need for larger, long‑term studies before it can be widely adopted.
Curious? Click through the gallery to discover how the story of depression treatments is evolving.