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Fatal familial insomnia: a rare inherited disorder

Rare disorder permanently prevents people from sleeping

Fatal familial insomnia: a rare inherited disorder
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Nicole Trovato
12/05/2025 14:45 ‧ 2 weeks ago | StarsInsider

HEALTH

Sleep disorders

Sleep is essential for our physical and mental well-being. And, yet, the Sleep Foundation estimates that 50 to 70 million people in the US alone experience sleep disturbances, with insomnia, sleep apnea, and narcolepsy being the most common. But while these conditions can significantly impact daily life, they pale in comparison to the devastating effects of fatal familial insomnia (FFI).

This extremely rare genetic disorder progressively robs individuals of the ability to sleep, leading to a fast decline in physical and mental health. Intrigued? Click through to learn more about this debilitating disorder and the ongoing efforts to find a cure.

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