Seasonal sniffles or year-round misery? The Asthma and Allergy Foundation of America’s 2025 Allergy Capitals report ranks the worst US cities for allergy sufferers, based on pollen levels, medication usage, and access to specialists. The results might surprise you: a Midwest city takes the top spot, while the South and parts of California see growing challenges. Whether you live in one of these areas or plan to visit, it’s worth knowing what you're up against.
Click on to see which cities made the list.